I have the same issue as I've got a set of keys for my place as well as my office plus a flash drive. I live in a city so neither hiding my flash drive in my car nor my house keys in a rock are viable options. While I wasn't originally a big proponent of a key holder, I would recommend you look into it. Here's an example by Mont Blanc.

If you have thirty-plus keys you'll still have a bulge, but by carrying keys and a flash in this, it will keep them relatively flat and organized. My girlfriend bought me this for the same problem you're having and I've found it makes it a lot less cumbersome to have my keys in my pocket instead of her bag.

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The Tumi Valet Key

It's nice because you can remove a ring, I use it for a spare set of car keys.

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I was looking at this product a couple years ago and it puts all your keys into a single fob. I've not got around to purchasing it as I didn't have enough keys to make this purchase worth it. But I thought I would just throw the idea out to you.

www.key-port.com

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For your flash drive, check out the Lacie flashkey, its a flash drive, and its a key! Best of all the slim formfactor and durable design are made to fit on your keychain.

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There is a simple way to keep keys off of the bottom of your pocket. http://www.clip-money.com has a small money clip with a hole milled in the bottom. You could make something like this yourself and use it to HANG the keys from top of pocket so they do not bunch up in the bottom

This is also explained in a blog http:www.clip-money.com/blog/?p=4

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